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KMID : 0861020030180040255
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Korea Journal of Herbology
2003 Volume.18 No. 4 p.255 ~ p.262
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Isolation of Novel Glucosyltransferase and Tyrosinase Inhibitor from the Roots of Korean Sanguisorbae officinalis L.
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Abstract
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Objectives : The study was experimented anti-plaque and whitening efficiency of the roots of Sanquisorbae sfficinalis L.
Methods : We identificated novel procyanidin structure established by thiolysis, desulfurization, tannase reaction, methylation and spectroscopic analysis, The physiological activity of anti-plaque and whitening efficiency was evaluated.
Results : The chemical structure was identified for procyanidin B-3 3-0-gallate containing the dimeric flavan-&oh, gallate and molecular weight was 792[M-H]- by FAB-MS negative ion method. The inhibitory effect on the glucosyltransferase and tyrosinase activity was investigated, novel compound showed complete inhibition at 0.75mM on the glucosyltransferase and tyrosinase was inhibited about 50% at 1001.1M.
Conclusion : The roots of Sanguisorbae @citmlis were expected functional agents for anti-plaque and whitening.
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